Prognostic significance of the urokinase plasminogen activator system in tissue and serum of dogs with appendicular osteosarcoma

Urokinase plasminogen activator (uPA) and its receptor uPAR promote cancer invasion and metastasis and are emerging therapeutic targets in both human and canine malignancies. While their clinical significance is well-characterized in multiple human tumor types, studies investigating their roles in o...

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Bibliographic Details
Main Authors: Arata Matsuyama, Geoffrey A. Wood, Rachael Speare, Courtney R. Schott, Anthony J. Mutsaers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522282/?tool=EBI