Enhanced Adipose Expression of Interferon Regulatory Factor (IRF)-5 Associates with the Signatures of Metabolic Inflammation in Diabetic Obese Patients

Enhanced Adipose Expression of Interferon Regulatory Factor (IRF)-5 Associates with the Signatures of Metabolic Inflammation in Diabetic Obese Patients

Interferon regulatory factors (IRFs) are emerging as the metabolic transcriptional regulators in obesity/type-2 diabetes (T2D). IRF5 is implicated with macrophage polarization toward the inflammatory M1-phenotype, nonetheless, changes in the adipose expression of IRF5 in T2D and relationship of thes...

Full description

Bibliographic Details
Main Authors: Sardar Sindhu, Shihab Kochumon, Reeby Thomas, Abdullah Bennakhi, Fahd Al-Mulla, Rasheed Ahmad
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
interferon regulatory factor-5
type-2 diabetes
obesity
adipose tissue
metabolic inflammation
Online Access:https://www.mdpi.com/2073-4409/9/3/730

Internet

https://www.mdpi.com/2073-4409/9/3/730

Similar Items