Robust memory humoral immune response to SARS-CoV-2 in the tonsils of adults and children

BackgroundAdaptive humoral immunity against SARS-CoV-2 has mainly been evaluated in peripheral blood. Human secondary lymphoid tissues (such as tonsils) contain large numbers of plasma cells that secrete immunoglobulins at mucosal sites. Yet, the role of mucosal memory immunity induced by vaccines o...

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Bibliographic Details
Main Authors: Tarfa A. Altorki, Rwaa H. Abdulal, Bandar A. Suliman, Talal M. Aljeraisi, Asem Alsharef, Wesam H. Abdulaal, Mohamed A. Alfaleh, Abdullah A. Algaissi, Rowa Y. Alhabbab, Hani Ozbak, Hamza Mohammed Eid, Yahya Ahmad Almutawif, Xuguang Li, Mohammed W. Al-Rabia, Qibo Zhang, Ahmed Bakur Mahmoud, Waleed H. Mahallawi, Anwar M. Hashem
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1291534/full