Striatal Synaptic Dysfunction in Dystonia and Levodopa-Induced Dyskinesia

Striatal Synaptic Dysfunction in Dystonia and Levodopa-Induced Dyskinesia

This review provides an overview of the synaptic dysfunctions of neuronal circuits and underlying neurochemical alterations observed in the hyperkinetic movement disorders, dystonia and dyskinesia. These disorders exhibit similar changes in expression of synaptic plasticity and neuromodulation. This...

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Bibliographic Details
Main Authors: Mariangela Scarduzio, Ellen J. Hess, David G. Standaert, Karen L. Eskow Jaunarajs
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
L-DOPA-induced dyskinesia
Dystonia
Synaptic dysfunction
Synaptic plasticity
Neurotransmitters
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996122000419

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http://www.sciencedirect.com/science/article/pii/S0969996122000419

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