The Protective Effects of IL-31RA Deficiency During Bleomycin-Induced Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis (IPF) is a severe fibrotic lung disease characterized by excessive collagen deposition and progressive decline in lung function. Th2 T cell-derived cytokines including IL-4 and IL-13 have been shown to contribute to inflammation and fibrotic remodeling in multiple tissu...

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Bibliographic Details
Main Authors: Dan J. K. Yombo, Varshini Odayar, Nishant Gupta, Anil G. Jegga, Satish K. Madala
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.645717/full