Effects of small interfering RNAs targeting fascin on human esophageal squamous cell carcinoma cell lines

<p>Abstract</p> <p>Background</p> <p>Fascin induces membrane protrusions and cell motility. Fascin overexpression was associated with poor prognosis, and its downregulation reduces cell motility and invasiveness in esophageal squamous cell carcinoma (ESCC). Using a stab...

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Bibliographic Details
Main Authors: Garcia Jose, Martorell Miguel, Sato Fumiaki, Tsunoda Shigeru, Iwai Akira, Nagayama Satoshi, Hashimoto Yosuke, Ito Tetsuo, Ortiz Cristian M, Perez Ana, Shimada Yutaka
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Diagnostic Pathology
Online Access:http://www.diagnosticpathology.org/content/5/1/41