Blood–Brain Barrier Integrity Is Perturbed in a <i>Mecp2</i>-Null Mouse Model of Rett Syndrome

Blood–Brain Barrier Integrity Is Perturbed in a <i>Mecp2</i>-Null Mouse Model of Rett Syndrome

Rett syndrome (RTT, online MIM 312750) is a devastating neurodevelopmental disorder characterized by motor and cognitive disabilities. It is mainly caused by pathogenetic variants in the X-linked <i>MECP2</i> gene, encoding an epigenetic factor crucial for brain functioning. Despite inte...

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Bibliographic Details
Main Authors: Giuseppe Pepe, Salvatore Fioriniello, Federico Marracino, Luca Capocci, Vittorio Maglione, Maurizio D’Esposito, Alba Di Pardo, Floriana Della Ragione
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomolecules
Subjects:
Rett syndrome
blood–brain barrier
MeCP2
neurodevelopmental disorder
autism spectrum disorder
Online Access:https://www.mdpi.com/2218-273X/13/4/606

Internet

https://www.mdpi.com/2218-273X/13/4/606

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