Improving automatic GO annotation with semantic similarity

Improving automatic GO annotation with semantic similarity

Abstract Background Automatic functional annotation of proteins is an open research problem in bioinformatics. The growing number of protein entries in public databases, for example in UniProtKB, poses challenges in manual functional annotation. Manual annotation requires expert human curators to se...

Full description

Bibliographic Details
Main Authors: Bishnu Sarker, Navya Khare, Marie-Dominique Devignes, Sabeur Aridhi
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Bioinformatics
Subjects:
Protein function annotation
Domain similarity network
Gene ontology annotation
Label propagation
Semantic similarity
GrAPFI
Online Access:https://doi.org/10.1186/s12859-022-04958-7

Internet

https://doi.org/10.1186/s12859-022-04958-7

Similar Items