Cooperativity, Specificity, and Evolutionary Stability of Polycomb Targeting in Drosophila

Cooperativity, Specificity, and Evolutionary Stability of Polycomb Targeting in Drosophila

Summary: Metazoan genomes are partitioned into modular chromosomal domains containing active or repressive chromatin. In flies, Polycomb group (PcG) response elements (PREs) recruit PHO and other DNA-binding factors and act as nucleation sites for the formation of Polycomb repressive domains. The se...

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Bibliographic Details
Main Authors: Bernd Schuettengruber, Noa Oded Elkayam, Tom Sexton, Marianne Entrevan, Shani Stern, Aubin Thomas, Eitan Yaffe, Hugues Parrinello, Amos Tanay, Giacomo Cavalli
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714007645

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http://www.sciencedirect.com/science/article/pii/S2211124714007645

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