Fluorescence Lifetime Imaging of Human Sub-RPE Calcification In Vitro Following Chlortetracycline Infusion

Fluorescence Lifetime Imaging of Human Sub-RPE Calcification In Vitro Following Chlortetracycline Infusion

We have shown that all sub-retinal pigment epithelial (sub-RPE) deposits examined contain calcium phosphate minerals: hydroxyapatite (HAP), whitlockite (Wht), or both. These typically take the form of ca. 1 μm diameter spherules or >10 μm nodules and appear to be involved in the development and p...

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Bibliographic Details
Main Authors: Kavita R. Hegde, Adam C. Puche, Henryk Szmacinski, Kristina Fuller, Krishanu Ray, Nikita Patel, Imre Lengyel, Richard B. Thompson
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
calcification
hydroxyapatite
retina
age-related macular degeneration
chlortetracycline
drusen
Online Access:https://www.mdpi.com/1422-0067/24/7/6421

Internet

https://www.mdpi.com/1422-0067/24/7/6421

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