Transcriptomic profiling reveals key early response genes during GDF6‐mediated differentiation of human adipose‐derived stem cells to nucleus pulposus cells

Transcriptomic profiling reveals key early response genes during GDF6‐mediated differentiation of human adipose‐derived stem cells to nucleus pulposus cells

Abstract Background Stem cell‐based therapies show promise as a means of repairing the degenerate intervertebral disc, with growth factors often used alongside cells to help direct differentiation toward a nucleus pulposus (NP)‐like phenotype. We previously demonstrated adipose‐derived stem cell (AS...

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Bibliographic Details
Main Authors: Hamish T. J. Gilbert, Francis E. J. Wignall, Leo Zeef, Judith A. Hoyland, Stephen M. Richardson
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:JOR Spine
Subjects:
adipose‐derived stem cell
differentiation
intervertebral disc
nucleus pulposus
regenerative medicine
transcriptomics
Online Access:https://doi.org/10.1002/jsp2.1315

Internet

https://doi.org/10.1002/jsp2.1315

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