RSV infection of humanized lung-only mice induces pathological changes resembling severe bronchiolitis and bronchopneumonia

RSV infection of humanized lung-only mice induces pathological changes resembling severe bronchiolitis and bronchopneumonia

Respiratory syncytial virus (RSV) is a substantial cause of severe lower respiratory tract infections in infants, young children, older adults, and immunocompromised individuals. There is a vital need for effective therapeutics to prevent and/or treat severe RSV infection in these high-risk individu...

Full description

Bibliographic Details
Main Authors: Chandrav De, Raymond J. Pickles, Wenbo Yao, Baolin Liao, Allison Boone, Rachel A. Cleary, J. Victor Garcia, Angela Wahl
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Virology
Subjects:
respiratory syncytial virus
RSV
humanized mice
LoM
human lung pathology
therapeutics
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2024.1380030/full

Internet

https://www.frontiersin.org/articles/10.3389/fviro.2024.1380030/full

Similar Items