Activation of peripheral TRPM8 mitigates ischemic stroke by topically applied menthol

Activation of peripheral TRPM8 mitigates ischemic stroke by topically applied menthol

Abstract Background No reports exist as to neuroprotective effects associated with topical activation of transient receptor potential melastatin 8 (TRPM8), a noted cold receptor. In the present study, we identified whether activating peripheral TRPM8 can be an adjuvant therapy for ischemic stroke. M...

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Bibliographic Details
Main Authors: Shiang-Suo Huang, Hsing-Hui Su, Szu-Yu Chien, Hsin-Yi Chung, Sih-Ting Luo, Yu-Ting Chu, Yi-Hsin Wang, Iona J. MacDonald, Hsun-Hua Lee, Yi-Hung Chen
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Neuroinflammation
Subjects:
Stroke
Acute ischemic stroke
Neuroprotection
TRPM8
Menthol
Topical
Online Access:https://doi.org/10.1186/s12974-022-02553-4

Internet

https://doi.org/10.1186/s12974-022-02553-4

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