Multinuclear Metal-Binding Ability of the N-Terminal Region of Human Copper Transporter Ctr1: Dependence Upon pH and Metal Oxidation State

Multinuclear Metal-Binding Ability of the N-Terminal Region of Human Copper Transporter Ctr1: Dependence Upon pH and Metal Oxidation State

The 14mer peptide corresponding to the N-terminal region of human copper transporter Ctr1 was used to investigate the intricate mechanism of metal binding to this plasma membrane permease responsible for copper import in eukaryotic cells. The peptide contains a high-affinity ATCUN Cu(II)/Ni(II)-sele...

Full description

Bibliographic Details
Main Authors: Maria Incoronata Nardella, Mariagrazia Fortino, Alessandra Barbanente, Giovanni Natile, Adriana Pietropaolo, Fabio Arnesano
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
Ctr1
copper
silver
metal transport
redox processes
NMR specroscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.897621/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.897621/full

Similar Items