Botulinum neurotoxin X lacks potency in mice and in human neurons

Botulinum neurotoxin X lacks potency in mice and in human neurons

ABSTRACTBotulinum neurotoxins (BoNTs) are a class of toxins produced by Clostridium botulinum (C. botulinum) and other species of Clostridia. BoNT/X is a putative novel botulinum neurotoxin identified through genome sequencing and capable of SNARE cleavage, but its neurotoxic potential in humans and...

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Bibliographic Details
Main Authors: Brieana M. Gregg, Takuhiro Matsumura, Travis G. Wentz, William H. Tepp, Marite Bradshaw, Pål Stenmark, Eric A. Johnson, Yukako Fujinaga, Sabine Pellett
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:mBio
Subjects:
botulinum neurotoxin
BoNT
Clostridium botulinum
BoNT/X
Online Access:https://journals.asm.org/doi/10.1128/mbio.03106-23

Internet

https://journals.asm.org/doi/10.1128/mbio.03106-23

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