Tissue-type Plasminogen Activator is a Neuroprotectant in the Central Nervous System
Tissue-type plasminogen activator (tPA) is a serine proteinase found not only in the intravascular space but also in a well-defined sub-set of neurons in the brain. TPA is rapidly released from neurons after either exposure to hypoxia or hypoglycemia in vitro, or the induction of cerebral ischemia...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2015-08-01
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Series: | Frontiers in Cellular Neuroscience |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00304/full |