Severe Impairment of TNF Post-transcriptional Regulation Leads to Embryonic Death

Severe Impairment of TNF Post-transcriptional Regulation Leads to Embryonic Death

Summary: Post-transcriptional regulation mechanisms control mRNA stability or translational efficiency via ribosomes, and recent evidence indicates that it is a major determinant of the accurate levels of cytokine mRNAs. Transcriptional regulation of Tnf has been well studied and found to be importa...

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Bibliographic Details
Main Authors: Elise Clayer, Destiny Dalseno, Andrew Kueh, Derek Lacey, Minhsuang Tsai, Elysa Carr, Verena C. Wimmer, Philippe Bouillet
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:iScience
Subjects:
Molecular Biology
Immunology
Developmental Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220309238

Internet

http://www.sciencedirect.com/science/article/pii/S2589004220309238

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