Determination and characterization of molecular heterogeneity and precision medicine strategies of patients with pancreatic cancer and pancreatic neuroendocrine tumor based on oxidative stress and mitochondrial dysfunction-related genes

Determination and characterization of molecular heterogeneity and precision medicine strategies of patients with pancreatic cancer and pancreatic neuroendocrine tumor based on oxidative stress and mitochondrial dysfunction-related genes

BackgroundMitochondria are significant both for cellular energy production and reactive oxygen/nitrogen species formation. However, the significant functions of mitochondrial genes related to oxidative stress (MTGs-OS) in pancreatic cancer (PC) and pancreatic neuroendocrine tumor (PNET) are yet to b...

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Bibliographic Details
Main Authors: Yougang Cui, Qihang Yuan, Junhong Chen, Jian Jiang, Hewen Guan, Ruiping Zhu, Ning Li, Wenzhi Liu, Changmiao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Endocrinology
Subjects:
pancreatic cancer
oxidative stress
mitochondrial dysfunction
molecular heterogeneity
precision medicine
pancreatic neuroendocrine tumor
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1127441/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1127441/full

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