Regulatory effects of sterols and bile acids on hepatic 3-hydroxy-3-methylglutaryl CoA reductase and cholesterol 7α-hydroxylase in the rat

Regulatory effects of sterols and bile acids on hepatic 3-hydroxy-3-methylglutaryl CoA reductase and cholesterol 7α-hydroxylase in the rat

Specific activities of the hepatic microsomal enzymes 3-hydroxy-3-methylglutaryl CoA (HMG CoA) reductase and cholesterol 7α-hydroxylase were studied in rats fed sterols and bile acids. The administration of bile acids (taurocholate, taurodeoxycholate, taurochenodeoxycholate) at a level of 1% of the...

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Bibliographic Details
Main Authors: S. Shefer, S. Hauser, V. Lapar, E.H. Mosbach
Format: Article
Language:English
Published: Elsevier 1973-09-01
Series:Journal of Lipid Research
Subjects:
microsomal enzymes
rate-limiting enzymes
taurocholate
taurodeoxycholate
taurochenodeoxycholate
sitostero
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520368632

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http://www.sciencedirect.com/science/article/pii/S0022227520368632

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