Amburana cearensis seed extract stimulates astrocyte glutamate homeostatic mechanisms in hippocampal brain slices and protects oligodendrocytes against ischemia

Amburana cearensis seed extract stimulates astrocyte glutamate homeostatic mechanisms in hippocampal brain slices and protects oligodendrocytes against ischemia

Abstract Background Stroke is a leading cause of death and disability worldwide. A major factor in brain damage following ischemia is excitotoxicity caused by elevated levels of the neurotransmitter glutamate. In the brain, glutamate homeostasis is a primary function of astrocytes. Amburana cearensi...

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Bibliographic Details
Main Authors: Rafael Short Ferreira, Paulo Roberto Ribeiro, Juliana Helena Castro e Silva, Juliana Bender Hoppe, Monique Marylin Alves de Almeida, Beatriz Correia de Lima Ferreira, Gustavo Borges Andrade, Suzana Braga de Souza, Luzimar Gonzaga Ferdandez, Maria de Fátima Dias Costa, Christianne Gazzana Salbego, Andrea Domenico Rivera, Aline Longoni, Adriano Martimbianco de Assis, Francesca Pieropan, José Cláudio Fonseca Moreira, Silvia Lima Costa, Arthur Morgan Butt, Victor Diogenes Amaral da Silva
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Amburana cearensis
Hippocampus
Oligodendrocyte
Astrocyte
Stroke
Online Access:https://doi.org/10.1186/s12906-023-03959-0

Internet

https://doi.org/10.1186/s12906-023-03959-0

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