Bookend: precise transcript reconstruction with end-guided assembly
Abstract We developed Bookend, a package for transcript assembly that incorporates data from different RNA-seq techniques, with a focus on identifying and utilizing RNA 5′ and 3′ ends. We demonstrate that correct identification of transcript start and end sites is essential for precise full-length t...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-06-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-022-02700-3 |