Paraspinal Muscle Health is Related to Fibrogenic, Adipogenic, and Myogenic Gene Expression in Patients with Lumbar Spine Pathology

Paraspinal Muscle Health is Related to Fibrogenic, Adipogenic, and Myogenic Gene Expression in Patients with Lumbar Spine Pathology

Abstract Background Lumbar spine pathology is a common feature of lower back and/or lower extremity pain and is associated with observable degenerative changes in the lumbar paraspinal muscles that are associated with poor clinical prognosis. Despite the commonly observed phenotype of muscle degener...

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Bibliographic Details
Main Authors: Brad Anderson, Angel Ordaz, Vinko Zlomislic, R. Todd Allen, Steven R. Garfin, Regula Schuepbach, Mazda Farshad, Simon Schenk, Samuel R. Ward, Bahar Shahidi
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Musculoskeletal Disorders
Subjects:
Low back pain
Skeletal muscle
Multifidus
Degeneration
Atrophy
Fatty infiltration
Online Access:https://doi.org/10.1186/s12891-022-05572-7

Internet

https://doi.org/10.1186/s12891-022-05572-7

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