Microfluidic-based human prostate-cancer-on-chip

Microfluidic-based human prostate-cancer-on-chip

Lack of adequate models significantly hinders advances in prostate cancer treatment, where resistance to androgen-deprivation therapies and bone metastasis remain as major challenges. Current in vitro models fail to faithfully mimic the complex prostate physiology. In vivo animal models can shed lig...

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Bibliographic Details
Main Authors: Linan Jiang, Hunain Khawaja, Shekha Tahsin, Tanjia A. Clarkson, Cindy K. Miranti, Yitshak Zohar
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
organ-on-chip
microfluidics
prostate cancer
stromal fibroblasts
cancer-associated fibroblasts (CAFs)
prostate tumor invasion
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1302223/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2024.1302223/full

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