Eupafolin suppresses TGF-β1-induced human lung fibroblasts differentiation by downregulating β-catenin/plasminogen activator inhibitor-1 signaling
The anti-fibrotic activity of flavonoids from Eupatorium lindleyanum DC (EL) remains unclear. Our results showed that flavones from the plant exerted a stronger inhibitory effect than flavonols, and eupafolin presented the highest activity on lung fibroblast differentiation. Eupafolin weakened the l...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-03-01
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| Series: | Pharmacological Research - Modern Chinese Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667142522000173 |