Inefficacy of N-acetylcysteine in mitigating cue-induced amphetamine-seeking
Glutamatergic imbalances are characteristic of SUDs. Astrocytic and neuronal transporters help regulate glutamate homeostasis and disruptions in this homeostasis engender SUD. The cysteine-glutamate exchanger (xCT) is primarily localized on astrocytes and maintains glutamate concentrations. This pro...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | Addiction Neuroscience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772392523000627 |