Inefficacy of N-acetylcysteine in mitigating cue-induced amphetamine-seeking

Glutamatergic imbalances are characteristic of SUDs. Astrocytic and neuronal transporters help regulate glutamate homeostasis and disruptions in this homeostasis engender SUD. The cysteine-glutamate exchanger (xCT) is primarily localized on astrocytes and maintains glutamate concentrations. This pro...

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Bibliographic Details
Main Authors: Troy D. Fort, Mary E. Cain
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Addiction Neuroscience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772392523000627