Heat Shock Protein 90 Regulates the Activity of Histone Deacetylase Sir2 in Plasmodium falciparum

Heat Shock Protein 90 Regulates the Activity of Histone Deacetylase Sir2 in Plasmodium falciparum

ABSTRACT Sir2 protein of Plasmodium falciparum has been implicated to play crucial roles in the silencing of subtelomeric var genes and rRNA. It is also involved in telomere length maintenance. Epigenetic regulation of PfSIR2 transcription occurs through a direct participation of the molecular chape...

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Bibliographic Details
Main Authors: Wahida Tabassum, Mrinnanda Bhattacharya, Sayan Bakshi, Mrinal Kanti Bhattacharyya
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:mSphere
Subjects:
PfSir2
PfHsp90
chaperone
var gene expression
antigenic variation
malaria
Online Access:https://journals.asm.org/doi/10.1128/msphere.00329-22

Internet

https://journals.asm.org/doi/10.1128/msphere.00329-22

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