Cellular Transcriptomics of Carboplatin Resistance in a Metastatic Canine Osteosarcoma Cell Line

Cellular Transcriptomics of Carboplatin Resistance in a Metastatic Canine Osteosarcoma Cell Line

Osteosarcoma prognosis has remained unchanged for the past three decades. In both humans and canines, treatment is limited to excision, radiation, and chemotherapy. Chemoresistance is the primary cause of treatment failure, and the trajectory of tumor evolution while under selective pressure from tr...

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Bibliographic Details
Main Authors: McKaela A. Hodge, Tasha Miller, Marcus A. Weinman, Brandan Wustefeld-Janssens, Shay Bracha, Brian W. Davis
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Genes
Subjects:
osteosarcoma
chemoresistance
tumor trajectory
EMT
tumor microenvironment
Online Access:https://www.mdpi.com/2073-4425/14/3/558

Internet

https://www.mdpi.com/2073-4425/14/3/558

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