T cell chemo-vaccination effects after repeated mucosal SHIV exposures and oral pre-exposure prophylaxis.

T cell chemo-vaccination effects after repeated mucosal SHIV exposures and oral pre-exposure prophylaxis.

Pre-exposure prophylaxis (PrEP) with anti-viral drugs is currently in clinical trials for the prevention of HIV infection. Induction of adaptive immune responses to virus exposures during anti-viral drug administration, i.e., a "chemo-vaccination" effect, could contribute to PrEP efficacy....

Full description

Bibliographic Details
Main Authors: Ellen N Kersh, Debra R Adams, Ae S Youngpairoj, Wei Luo, Qi Zheng, Mian-er Cong, Wutyi Aung, James Mitchell, Ron Otten, R Michael Hendry, Walid Heneine, Janet McNicholl, J Gerardo Garcia-Lerma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3082568?pdf=render

Internet

http://europepmc.org/articles/PMC3082568?pdf=render

Similar Items