Transposable elements regulate thymus development and function

Transposable elements regulate thymus development and function

Transposable elements (TEs) are repetitive sequences representing ~45% of the human and mouse genomes and are highly expressed by medullary thymic epithelial cells (mTECs). In this study, we investigated the role of TEs on T-cell development in the thymus. We performed multiomic analyses of TEs in h...

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Detaylı Bibliyografya
Asıl Yazarlar: Jean-David Larouche, Céline M Laumont, Assya Trofimov, Krystel Vincent, Leslie Hesnard, Sylvie Brochu, Caroline Côté, Juliette F Humeau, Éric Bonneil, Joel Lanoix, Chantal Durette, Patrick Gendron, Jean-Philippe Laverdure, Ellen R Richie, Sébastien Lemieux, Pierre Thibault, Claude Perreault
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: eLife Sciences Publications Ltd 2024-04-01
Seri Bilgileri:eLife
Konular:
transposable elements
thymus
central tolerance
thymic epithelial cells
plasmacytoid dendritic cells
Online Erişim:https://elifesciences.org/articles/91037

Internet

https://elifesciences.org/articles/91037

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