Fusobacterium necrophorum Promotes Apoptosis and Inflammatory Cytokine Production Through the Activation of NF-κB and Death Receptor Signaling Pathways

Fusobacterium necrophorum Promotes Apoptosis and Inflammatory Cytokine Production Through the Activation of NF-κB and Death Receptor Signaling Pathways

Fusobacterium necrophorum can cause liver abscess, foot rot in ruminants, and Lemire syndrome in humans, Also, its virulence factors can induce the apoptosis of macrophages and neutrophils. However, the detailed mechanism has not been fully clarified. This study investigated the mechanisms of apopto...

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Bibliographic Details
Main Authors: Feng-Feng Wang, Peng-Yu Zhao, Xian-Jing He, Kai Jiang, Tian-Shuo Wang, Jia-Wei Xiao, Dong-Bo Sun, Dong-Hua Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Apoptosis
Fusobacterium necrophorum
inflammatory
RAW246.7 cells
sheep neutrophil
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.827750/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2022.827750/full

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