Data-driven prediction and design of bZIP coiled-coil interactions.

Data-driven prediction and design of bZIP coiled-coil interactions.

Selective dimerization of the basic-region leucine-zipper (bZIP) transcription factors presents a vivid example of how a high degree of interaction specificity can be achieved within a family of structurally similar proteins. The coiled-coil motif that mediates homo- or hetero-dimerization of the bZ...

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Bibliographic Details
Main Authors: Vladimir Potapov, Jenifer B Kaplan, Amy E Keating
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4335062?pdf=render

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http://europepmc.org/articles/PMC4335062?pdf=render

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