Data-driven prediction and design of bZIP coiled-coil interactions.
Selective dimerization of the basic-region leucine-zipper (bZIP) transcription factors presents a vivid example of how a high degree of interaction specificity can be achieved within a family of structurally similar proteins. The coiled-coil motif that mediates homo- or hetero-dimerization of the bZ...
Main Authors: | , , |
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Format: | Article |
Jezik: | English |
Izdano: |
Public Library of Science (PLoS)
2015-02-01
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Serija: | PLoS Computational Biology |
Online dostop: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004046&type=printable |