Rats with high aerobic capacity display enhanced transcriptional adaptability and upregulation of bile acid metabolism in response to an acute high‐fat diet

Rats with high aerobic capacity display enhanced transcriptional adaptability and upregulation of bile acid metabolism in response to an acute high‐fat diet

Abstract Rats selectively bred for the high intrinsic aerobic capacity runner (HCR) or low aerobic capacity runner (LCR) show pronounced differences in susceptibility for high‐fat/high sucrose (HFHS) diet‐induced hepatic steatosis and insulin resistance, replicating the protective effect of high aer...

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Bibliographic Details
Main Authors: Harrison D. Stierwalt, E. Matthew Morris, Adrianna Maurer, Udayan Apte, Kathryn Phillips, Tiangang Li, Grace M. E. Meers, Lauren G. Koch, Steven L. Britton, Greg Graf, R. Scott Rector, Kelly Mercer, Kartik Shankar, John P. Thyfault
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:Physiological Reports
Subjects:
aerobic capacity
bile acids
cholesterol
fatty liver
Online Access:https://doi.org/10.14814/phy2.15405

Internet

https://doi.org/10.14814/phy2.15405

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