Higher CD27+CD8+ T cells percentages during suppressive antiretroviral therapy predict greater subsequent CD4+ T cell recovery in treated HIV infection.

Higher CD27+CD8+ T cells percentages during suppressive antiretroviral therapy predict greater subsequent CD4+ T cell recovery in treated HIV infection.

HIV-mediated immune dysfunction may influence CD4(+) T cell recovery during suppressive antiretroviral therapy (ART). We analyzed cellular biomarkers of immunological inflammation, maturation, and senescence in HIV-infected subjects on early suppressive ART. We performed longitudinal analyses of per...

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Bibliographic Details
Main Authors: Lillian Seu, Gabriel M Ortiz, Lorrie Epling, Elizabeth Sinclair, Louise A Swainson, Urmila D Bajpai, Yong Huang, Steven G Deeks, Peter W Hunt, Jeffrey N Martin, Joseph M McCune
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3877182?pdf=render

Internet

http://europepmc.org/articles/PMC3877182?pdf=render

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