Construction of an ER stress-related prognostic signature for predicting prognosis and screening the effective anti-tumor drug in osteosarcoma

Construction of an ER stress-related prognostic signature for predicting prognosis and screening the effective anti-tumor drug in osteosarcoma

Abstract Background Osteosarcoma is the most common malignant primary bone tumor in infants and adolescents. The lack of understanding of the molecular mechanisms underlying osteosarcoma progression and metastasis has contributed to a plateau in the development of current therapies. Endoplasmic reti...

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Bibliographic Details
Main Authors: Weidong Chen, Yan Liao, Pengxiao Sun, Jian Tu, Yutong Zou, Ji Fang, Ziyun Chen, Hongbo Li, Junkai Chen, Yuzhong Peng, Lili Wen, Xianbiao Xie
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Translational Medicine
Subjects:
Osteosarcoma
ER stress
Prognostic signature
STC2
Tumor microenvironment
ISOX
Online Access:https://doi.org/10.1186/s12967-023-04794-0

Internet

https://doi.org/10.1186/s12967-023-04794-0

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