Phenotypically concordant distribution of pick bodies in aphasic versus behavioral dementias

Phenotypically concordant distribution of pick bodies in aphasic versus behavioral dementias

Abstract Pick’s disease (PiD) is a subtype of the tauopathy form of frontotemporal lobar degeneration (FTLD-tau) characterized by intraneuronal 3R-tau inclusions. PiD can underly various dementia syndromes, including primary progressive aphasia (PPA), characterized by an isolated and progressive imp...

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Bibliographic Details
Main Authors: Allegra Kawles, Rachel Keszycki, Grace Minogue, Antonia Zouridakis, Ivan Ayala, Nathan Gill, Alyssa Macomber, Vivienne Lubbat, Christina Coventry, Emily Rogalski, Sandra Weintraub, Qinwen Mao, Margaret E. Flanagan, Hui Zhang, Rudolph Castellani, Eileen H. Bigio, M.-Marsel Mesulam, Changiz Geula, Tamar Gefen
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Acta Neuropathologica Communications
Subjects:
Pick’s disease
Stereology
Primary progressive aphasia
Behavioral variant frontotemporal dementia
Frontotemporal lobar degeneration
Tau
Online Access:https://doi.org/10.1186/s40478-024-01738-7

Internet

https://doi.org/10.1186/s40478-024-01738-7

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