Progression of squamous cell carcinoma is regulated by miR-139-5p/CXCR4

miR-139-5p has a tumor suppressor effect in some cancers and negatively regulates CXCR4. To this end, we examined the expression and mechanism of of action of miR-139-5p and CXCR4 in oral squamous cell carcinoma (OSCC). miRNA-139-5p was down-regulated whereas CXCR4 was increased in tissues and cells...

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Bibliographic Details
Main Authors: Qian Jiang, Yiting Cao, Yating Qiu, Chenlin Li, Liu Liu, Guangzhou Xu
Format: Article
Language:English
Published: IMR Press 2020-06-01
Series:Frontiers in Bioscience-Landmark
Subjects:
Online Access:https://www.imrpress.com/journal/FBL/25/9/10.2741/4875