Co-cultures of cerebellar slices from mice with different reelin genetic backgrounds as a model to study cortical lamination [version 2; peer review: 2 approved]

Background: Reelin has fundamental functions in the developing and mature brain. Its absence gives rise to the Reeler mouse phenotype. In reln(-/-) mutants, neurons are mispositioned in layered brain areas such as the cerebellar cortex. We demonstrate that in cultured cerebellar slices, one can redu...

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Bibliographic Details
Main Authors: Adalberto Merighi, Laura Lossi
Format: Article
Language:English
Published: F1000 Research Ltd 2023-10-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/11-1183/v2