Co-cultures of cerebellar slices from mice with different reelin genetic backgrounds as a model to study cortical lamination [version 2; peer review: 2 approved]
Background: Reelin has fundamental functions in the developing and mature brain. Its absence gives rise to the Reeler mouse phenotype. In reln(-/-) mutants, neurons are mispositioned in layered brain areas such as the cerebellar cortex. We demonstrate that in cultured cerebellar slices, one can redu...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2023-10-01
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Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/11-1183/v2 |