Two-component system RgfA/C activates the fbsB gene encoding major fibrinogen-binding protein in highly virulent CC17 clone group B Streptococcus.

Two-component system RgfA/C activates the fbsB gene encoding major fibrinogen-binding protein in highly virulent CC17 clone group B Streptococcus.

Group B streptococcus (GBS) strains with the highest ability to bind to human fibrinogen belong to the highly invasive clonal complex (CC) 17. To investigate the fibrinogen-binding mechanisms of CC17 strains, we determined the prevalence of fibrinogen-binding genes (fbsA and fbsB), and fbs regulator...

Full description

Bibliographic Details
Main Authors: Rim Al Safadi, Laurent Mereghetti, Mazen Salloum, Marie-Frédérique Lartigue, Isabelle Virlogeux-Payant, Roland Quentin, Agnès Rosenau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3033900?pdf=render

Internet

http://europepmc.org/articles/PMC3033900?pdf=render

Similar Items