Identification of BACE-1 Inhibitors against Alzheimer’s Disease through E-Pharmacophore-Based Virtual Screening and Molecular Dynamics Simulation Studies: An Insilco Approach
Alzheimer is a severe memory and cognitive impairment neurodegenerative disease that is the most common cause of dementia worldwide and characterized by the pathological accumulation of tau protein and amyloid-beta peptides. In this study, we have developed E-pharmacophore modeling to screen the eMo...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/4/952 |