Identification of BACE-1 Inhibitors against Alzheimer’s Disease through E-Pharmacophore-Based Virtual Screening and Molecular Dynamics Simulation Studies: An Insilco Approach

Identification of BACE-1 Inhibitors against Alzheimer’s Disease through E-Pharmacophore-Based Virtual Screening and Molecular Dynamics Simulation Studies: An Insilco Approach

Alzheimer is a severe memory and cognitive impairment neurodegenerative disease that is the most common cause of dementia worldwide and characterized by the pathological accumulation of tau protein and amyloid-beta peptides. In this study, we have developed E-pharmacophore modeling to screen the eMo...

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Bibliographic Details
Main Author:	Kumarappan Chidambaram
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Series:	Life
Subjects:	Alzheimer’s BACE-1 E-pharmacophore molecular docking molecular dynamics simulation pharmacophore-based virtual screening
Online Access:	https://www.mdpi.com/2075-1729/13/4/952

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