Three-dimensional hepatocyte culture system for the study of Echinococcus multilocularis larval development.

Hepatocyte-based metacestode culture is an attractive method to study alveolar echinococcosis (AE), but it is limited by the relatively short lifespan of cultured hepatocytes in maintaining their normal function.We describe a three-dimensional (3D) hepatic culture system developed from co-cultured h...

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Bibliographic Details
Main Authors: Li Li, Bing Chen, Hongbin Yan, Yannan Zhao, Zhongzi Lou, Jianqiu Li, Baoquan Fu, Xingquan Zhu, Donald P McManus, Jianwu Dai, Wanzhong Jia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5868855?pdf=render