HAHap: a read-based haplotyping method using hierarchical assembly

Background The need for read-based phasing arises with advances in sequencing technologies. The minimum error correction (MEC) approach is the primary trend to resolve haplotypes by reducing conflicts in a single nucleotide polymorphism-fragment matrix. However, it is frequently observed that the so...

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Bibliographic Details
Main Authors: Yu-Yu Lin, Ping Chun Wu, Pei-Lung Chen, Yen-Jen Oyang, Chien-Yu Chen
Format: Article
Language:English
Published: PeerJ Inc. 2018-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/5852.pdf