Distinct gene expression signatures comparing latent tuberculosis infection with different routes of Bacillus Calmette-Guérin vaccination

Abstract Tuberculosis remains an international health threat partly because of limited protection from pulmonary tuberculosis provided by standard intradermal vaccination with Bacillus of Calmette and Guérin (BCG); this may reflect the inability of intradermal vaccination to optimally induce pulmona...

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Bibliographic Details
Main Authors: Richard F. Silver, Mei Xia, Chad E. Storer, Jessica R. Jarvela, Michelle C. Moyer, Azra Blazevic, David A. Stoeckel, Erin K. Rakey, Jan M. Tennant, Johannes B. Goll, Richard D. Head, Daniel F. Hoft
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44136-8