CYP2C19 Gene Profiling as a Tool for Personalized Stress Ulcer Prophylaxis With Proton Pump Inhibitors in Critically Ill Patients - Recommendations Proposal

CYP2C19 Gene Profiling as a Tool for Personalized Stress Ulcer Prophylaxis With Proton Pump Inhibitors in Critically Ill Patients - Recommendations Proposal

To this date, there are no recommendations for personalized stress ulcer prophylaxis (SUP) in critical care that would take the patient's individual genetic predispositions into account. Of drugs used for this purpose, proton pump inhibitors (PPIs) are the first-choice drugs in intensive care u...

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Bibliographic Details
Main Authors: Petra Bořilová Linhartová, Ondřej Zendulka, Jaroslav Janošek, Natálie Mlčůchová, Michaela Cvanová, Zdeněk Daněk, Radek Kroupa, Ladislava Bartošová, Břetislav Lipový
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Medicine
Subjects:
critical care
personalized therapy
stress ulcer prophylaxis
proton pump inhibitors
pharmacogenetics
gene polymorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.854280/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.854280/full

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