Hypoxia-induced circWSB1 promotes breast cancer progression through destabilizing p53 by interacting with USP10

Abstract Background Hypoxia has long been considered as a hallmark of solid tumors and is closely associated with tumor progression. Circular RNAs (circRNAs) have been identified as a critical modulator in various cancers. However, the connections between hypoxia and circRNAs are largely unknown. Me...

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Bibliographic Details
Main Authors: Rui Yang, Hang Chen, Lei Xing, Bin Wang, Mengting Hu, Xiaoqiang Ou, Hong Chen, Yumei Deng, Dawei Liu, Rong Jiang, Junxia Chen
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Molecular Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12943-022-01567-z