GATM, the human ortholog of the mouse imprinted Gatm gene, escapes genomic imprinting in placenta

The GATM gene encodes L-arginine:glycine amidinotransferase, which catalyzes the conversion of L-arginine into guanidinoacetate, the rate-limiting step in the synthesis of creatine. Since, deficiencies in creatine synthesis and transport lead to certain forms of mental retardation in human, the huma...

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Detalles Bibliográficos
Main Authors: Toshinobu Miyamoto, Kazuo Sengoku, Hiroaki Hayashi, Yoshihito Sasaki, Yoshihiro Jinno, Mutsuo Ishikawa
Formato: Artigo
Idioma:English
Publicado: Sociedade Brasileira de Genética 2005-03-01
Series:Genetics and Molecular Biology
Subjects:
Acceso en liña:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000100008