Whole genome sequencing reveals the independent clonal origin of multifocal ileal neuroendocrine tumors

Whole genome sequencing reveals the independent clonal origin of multifocal ileal neuroendocrine tumors

Abstract Background Small intestinal neuroendocrine tumors (SI-NETs) are the most common neoplasms of the small bowel. The majority of tumors are located in the distal ileum with a high incidence of multiple synchronous primary tumors. Even though up to 50% of SI-NET patients are diagnosed with mult...

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Bibliographic Details
Main Authors: Netta Mäkinen, Meng Zhou, Zhouwei Zhang, Yosuke Kasai, Elizabeth Perez, Grace E. Kim, Chrissie Thirlwell, Eric Nakakura, Matthew Meyerson
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Genome Medicine
Subjects:
Small bowel
Small intestinal neuroendocrine tumors
Multifocality
Whole genome sequencing
Independent clonal origin
Online Access:https://doi.org/10.1186/s13073-022-01083-1

Internet

https://doi.org/10.1186/s13073-022-01083-1

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