Antitumor effect of anti-vascular therapy with STING agonist depends on the tumor microenvironment context

Antitumor effect of anti-vascular therapy with STING agonist depends on the tumor microenvironment context

IntroductionTargeting tumor vasculature is an efficient weapon to fight against cancer; however, activation of alternative pathways to rebuild the disrupted vasculature leads to rapid tumor regrowth. Immunotherapy that exploits host immune cells to elicit and sustain potent antitumor response has em...

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Bibliographic Details
Main Authors: Justyna Czapla, Alina Drzyzga, Sybilla Matuszczak, Tomasz Cichoń, Marek Rusin, Magdalena Jarosz-Biej, Ewelina Pilny, Ryszard Smolarczyk
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Oncology
Subjects:
STING signaling
anti-vascular therapy
immunotherapy
immune checkpoint inhibitors
the tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1249524/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1249524/full

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