The SUMOylation of Human Cytomegalovirus Capsid Assembly Protein Precursor (UL80.5) Affects Its Interaction with Major Capsid Protein (UL86) and Viral Replication

Human Cytomegalovirus Capsid Assembly Protein Precursor (pAP, UL80.5) plays a key role in capsid assembly by forming an internal protein scaffold with Major Capsid Protein (MCP, UL86) and other capsid subunits. In this study, we revealed UL80.5 as a novel SUMOylated viral protein. We confirmed that...

Full description

Bibliographic Details
Main Authors: Zhigang Zhang, Sisi Xia, Zhigang Wang, Nina Yin, Jun Chen, Luyao Shao
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/4/931