MPS1 is involved in the HPV16-E7-mediated centrosomes amplification

Abstract Background It has been reported that the oncoprotein E7 from human papillomavirus type 16 (HPV16-E7) can induce the excessive synthesis of centrosomes through the increase in the expression of PLK4, which is a transcriptional target of E2F1. On the other hand, it has been reported that incr...

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Main Authors: Yair Alfaro-Mora, Guadalupe Domínguez-Gómez, Rodrigo E. Cáceres-Gutiérrez, Laura Tolentino-García, Luis A. Herrera, Clementina Castro-Hernández, Rosa María Bermúdez-Cruz, José Díaz-Chávez
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Cell Division
Subjects:
Online Access:https://doi.org/10.1186/s13008-021-00074-9